Thomas Clark Trimble III (August 27, 1878 – July 6, 1965) was a United States federal judge.
Born in Lonoke, Arkansas, Trimble received an LL.B. from the University of Arkansas School of Law in 1902. He was in private practice in Lonoke from 1902 to 1937.
On June 17, 1937, Trimble was nominated by President Franklin D. Roosevelt to a seat on the United States District Court for the Eastern District of Arkansas vacated by John E. Martineau. Trimble was confirmed by the United States Senate, and received his commission, on June 18, 1937. He served as chief judge from 1948 to 1957 and assumed senior status on January 14, 1957. Trimble's served in that capacity until his death, in 1965, in Little Rock, Arkansas.
He married Elsie Jane Walls, they were the parents of daughter Elsijane Trimble Roy. She also was appointed to a seat on United States District Court for the Eastern District of Arkansas in 1977.